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The Top Line The Top Line Fierce Life Sciences R&B Music News Today | 2 Min News | The Daily News Now! R&B Music News Today | 2 Min News | The Daily News Now! The Daily News Now! Crime Stories with Nancy Grace Crime Stories with Nancy Grace iHeartPodcasts and CrimeOnline RTL Matin RTL Matin RTL Rebel News Podcast Rebel News Podcast Rebel News True Crime Today | Daily True Crime News & Interviews True Crime Today | Daily True Crime News & Interviews Real Story Media Las noticias de la SER Las noticias de la SER Felipe Areal The World This Hour The World This Hour Vohay Noticentro Noticentro Audio Centro True Crime Podcast 2026 - Police Interrogations, 911 Calls and True Police Stories Podcast True Crime Podcast 2026 - Police Interrogations, 911 Calls and True Police Stories Podcast True Crime Podcast 2026 The Vault: The Epstein Files The Vault: The Epstein Files Bobby Capucci Just Say KNOW with Maria, Green Bee Life Just Say KNOW with Maria, Green Bee Life KCAA Radio Radio Hamburg Nachrichten Radio Hamburg Nachrichten Radio Hamburg Israel Today: Ongoing War Report Israel Today: Ongoing War Report Noa Levi InvestTalk InvestTalk Hosts Justin Klein & Luke Guerrero, CFA | Wealth Managers and Investment Advisors Siste nytt fra VG Siste nytt fra VG VG Gali Tzhal (Galtaz) News - חדשות גלי צה"ל (גלצ) Gali Tzhal (Galtaz) News - חדשות גלי צה"ל (גלצ) mr. m4a Pittsburgh Penguins News Today | 2 Min News | The Daily News Now! Pittsburgh Penguins News Today | 2 Min News | The Daily News Now! The Daily News Now! ESPN Radio Fórmula ESPN Radio Fórmula Radio Fórmula Belfast News Today | 2 Min News | The Daily News Now! Belfast News Today | 2 Min News | The Daily News Now! The Daily News Now! Kan Hourly News כאן רשת ב חדשות - מהדורת השעה Kan Hourly News כאן רשת ב חדשות - מהדורת השעה Mr. Mp3 Providence News Today | 2 Min News | The Daily News Now! Providence News Today | 2 Min News | The Daily News Now! The Daily News Now! Beyond The Horizon Beyond The Horizon Bobby Capucci AP Newswatch: Top Stories from the Associated Press AP Newswatch: Top Stories from the Associated Press The Associated Press The Diddy Diaries The Diddy Diaries Bobby Capucci Political Capital with Rob Shaw Political Capital with Rob Shaw CHEK Podcasts The Von Haessler Doctrine The Von Haessler Doctrine Cox Media Group NZZ Akzent NZZ Akzent NZZ The Moscow Murders and More The Moscow Murders and More Bobby Capucci The Buckeye Scoop The Buckeye Scoop Buckeye Scoop Theology Central Theology Central Theology Central Media | Confessional Theology & Critical Analysis Frangela: The Final Word Frangela: The Final Word Frangela Duo Lehto's Law Lehto's Law Lehto's Law The Dallas Cowboys Mike Fisher 'Fish Report' The Dallas Cowboys Mike Fisher 'Fish Report' Fan Stream Sports, Bleav Bill Spadea Bill Spadea NJ 101.5 KJZZ's Sun Up KJZZ's Sun Up KJZZ 91.5FM Phoenix Hondelatte Raconte Hondelatte Raconte Europe 1
The Top Line

News

The Top Line

Fierce Life Sciences

A $10B deal, China trial scrutiny and highlights from ADA 2026

July 10, 2026 8:16am 24 min

This week on "The Top Line," we’re covering some of the biggest stories across biopharma before turning to one of the industry’s major scientific meetings of the summer. First, we discuss Vertex’s $10 billion acquisition...

The deal before the deal

June 26, 2026 8:22am 41 min

Big Pharma dealmaking has picked up, but the biotech path to a signed agreement is still anything but simple. In this episode, recorded at Fierce Biotech Week, Senior Editor James Waldron leads a discussion on the evolvi...

FDA Breakthrough Therapy and RMAT: Strategic Decisions That Can Accelerate Oncology Development (Sponsored)

June 22, 2026 7:00am 20 min

In this sponsored episode of The Top Line, host Stephanie Butler is joined by Sheila Plant, vice president of regulatory affairs at Allucent, to examine how FDA Breakthrough Therapy and RMAT designations can support more...

Ipsen R&D chief on pipeline discipline, partnerships and 2026 milestones

June 12, 2026 8:56am 15 min

In this episode of “The Top Line,” recorded on site at Fierce Biotech Week in Boston, Fierce’s Ayla Ellison sits down with Christelle Huguet, Ph.D., executive vice president and head of R&D at Ipsen, to discuss how the c...

Why MRD is becoming central to oncology drug development (Sponsored)

June 10, 2026 11:39am 18 min

In this sponsored episode of The Top Line, experts from Myriad Genetics join host Stephanie Butler to examine how tumor-informed molecular residual disease, or MRD, testing is beginning to redefine what early insight can...

Behind the headlines of ASCO 2026

June 05, 2026 8:56am 29 min

Each year, the global oncology community flocks to Chicago to convene at the American Society of Clinical Oncology’s annual meeting for a weekend of buzzy data drops, practice-changing posters and insightful sessions.   ...

Mesutoclax points to possible shift in high-risk MDS and AML (Sponsored)

June 03, 2026 8:15am 21 min

High‑risk MDS and AML continue to challenge clinicians, with limited durable responses and few options for older or treatment‑refractory patients. In this sponsored episode of The Top Line, host Stephanie Butler is joine...

Boston, China and the future of biotech

May 29, 2026 8:07am 35 min

Boston remains biotech's most influential hub, but the questions facing the region are increasingly global. Recorded live at Fierce Biotech Week in Boston, this panel discussion brings together Uli Stilz, senior advisor ...

Why direct-to-patient is the future of pharma access (Sponsored)

May 28, 2026 2:25pm 9 min

Direct-to-patient models are no longer an experiment - they're becoming a critical part of the modern prescription journey. In this sponsored episode of The Top Line, host Kelly Hogan talks with Jeremy Richardson, chief ...

BioAge CEO talks NLRP3 and ‘pipeline in a pill’ ambitions

May 22, 2026 9:04am 12 min

Recorded last week at Fierce Biotech Week in Boston, this episode of “The Top Line” features a conversation with Kristen Fortney, Ph.D., co-founder and CEO of BioAge Labs. In a conversation with Ayla Ellison, editor-in-c...

Designing an agentic, future‑ready tech roadmap for emerging pharma (Sponsored)

May 18, 2026 1:08pm 28 min

Emerging pharma organizations face unique technology challenges as they prepare for launch. Expectations for AI-enabled decision-making continue to rise, even as teams remain small and operate in highly regulated environ...

Health execs persevere in new policy landscape

May 15, 2026 8:22am 22 min

Despite a prolonged period of policy uncertainty in the U.S.—and the ripple effects across the global life sciences and healthcare industries—executives at health companies are still seeing opportunities amid the tumult....

Revisiting Pharma’s tariff reality

May 08, 2026 8:24am 15 min

After months of mixed messaging from the White House, the pharmaceutical industry has gained more clarity on the second Trump administration’s import tariff policy for drugs. While many of the industry’s biggest firms ha...

Setting a new standard in prefillable syringe systems (Sponsored)

May 07, 2026 11:25am 12 min

In this sponsored episode of The Top Line, host Kelly Hogan speaks with Dr. Bettine Boltres, director of scientific affairs, integrated systems at West Pharmaceutical Services, about the development of the West Synchrony...

Scaling theranostics through access, safety and trust (Sponsored)

May 04, 2026 7:00am 7 min

Theranostics is transforming cancer care, but scaling these treatments requires overcoming operational and workforce challenges. In this episode of The Top Line, Curium’s Mike Patterson discusses how access, safety and t...

A pivotal time for an RNA pioneer

May 01, 2026 7:49am 35 min

It’s a pivotal year for RNA therapeutics pioneer Ionis Pharmaceuticals.  After transitioning from a partnering model to a full-ownership strategy following the 2024 approval of Tryngolza, the company is expecting an FDA ...

Accelerating clinical trials with precision logistics (Sponsored)

April 27, 2026 8:00am 7 min

Speed, precision, and visibility are critical to clinical trial success, and logistics plays a central role in delivering all three. In this interview, Manishaa O’Brien, director of commercial operations at Marken UPS He...

Can Trump’s deal with the UK become a model for similar drug price agreements?

April 24, 2026 8:15am 21 min

President Donald Trump has struck a deal with the UK that exempts prescription drugs imported to the United States from tariffs for three years. In exchange, Britain’s National Health Service will pay 25% more for new dr...

Biomarkers are reshaping oncology trial design (Sponsored)

April 21, 2026 7:00am 14 min

Biomarkers are playing an increasingly critical role in shaping the future of oncology trials—and the pace of innovation is accelerating. In this sponsored episode of The Top Line, host Stephanie Butler sits down with Dr...

AI brings precision to pharma content decisions (Sponsored)

April 20, 2026 9:00am 9 min

Artificial intelligence is increasingly shaping how pharma companies approach content strategy and decision-making. In this episode of The Top Line, Kristen Pilkiewicz, EVP and executive creative director at Sound Health...

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